Congenital hyperinsulinism (CHI)

CHI is an ultra-rare genetic disease affecting newborns, infants and children that causes the insulin cells of the pancreas, called beta cells, to secrete too much insulin, leading to frequent, recurrent and often severe episodes of low glucose (hypoglycemia). In patients with CHI, this may result in cognitive disabilities.

Complex care, including continuous enteral feeding or intravenous glucose, can result in lengthy and frequent hospitalizations that make daily life difficult. More than half of CHI patients may be sub-optimally treated with current therapies. The most severely affected children may need to have their pancreas removed within months of birth to prevent hypoglycemia, which results in the development of life-long type 1 diabetes. The burden of managing CHI is significant for the affected children and their families and caregivers.

At any moment, his blood sugar can drop to a really dangerous level.

Crosby was born with CHI.

At any moment, his blood sugar can drop to a really dangerous level

Crosby was born with congenital hyperinsulinism (CHI): an ultra-rare genetic disorder that causes the insulin cells of the pancreas, called beta cells, to secrete too much insulin. The disorder may cause Crosby to have cognitive and physical disabilities if not treated adequately.