Gastrointestinal (GI) diseases

Diseases of the digestive system affect multiple organs, including the esophagus, stomach, small and large intestines as well as the liver, gallbladder and pancreas. More than 180 GI diseases affect many millions of people.

Some of these diseases have a high prevalence, such as ulcerative colitis, Crohn’s disease and irritable bowel syndrome (IBS), but the majority of the GI diseases affect smaller patient populations. There remains a significant need for innovation, as most GI diseases are not served well by current therapies.

We have a solid and advancing understanding of the molecular and cellular mechanisms dysregulated in GI diseases. Multiple regulatory peptides and secretory factors are produced by the gastrointestinal tract, and these represent high potential novel therapeutic targets.

*National Institutes of Health, U.S. Department of Health and Human Services. Opportunities and Challenges in Digestive Diseases Research: Recommendations of the National Commission on Digestive Diseases. Bethesda, MD: National Institutes of Health; 2009. NIH Publication 08–6514.

Going from 10 hours to 8 hours was the largest jump

Dependent on parenteral support to survive, Mike must connect to infusion equipment for eight hours a day, six days a week. Reducing the complexity – and time spent – for parenteral support enabled this driven college football coach to get back in the game.

My worst fear was to become what I am today: a short bowel patient

Marianne was diagnosed with cancer of the small intestine and became a short bowel patient. Today, she manages to live a life on home parenteral nutrition and works as a pastor. 

Depending on parenteral support to live

Diagnosed with short bowel syndrome at 13 years old, Will began receiving total parenteral support (PS), a lifesaving therapy for patients with intestinal failure that provides all the elements of nutrition and hydration needed to live via intravenous infusion.