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2008
28 August 2008: Announcement no. 2, 2008: Zealand Pharma today announced that Dr. David H...
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Product Pipeline
Zealand's Pipeline comprises 1 compound in phase III, 2 compounds in phase II, 3 compounds ...
2003
Eloff, B.C., Gilat, E., Wan, X., and Rosenbaum, D.S.:
Pharmacological Modulation of Cardiac Gap Junctions to Enhance Cardiac Conduction: Evidence Supporting a Novel Target for Antiarrhythmic Therapy.
Circulation, Dec 2003; 108: 3157 - 3163
Dhein, S., Larsen, B.D., Petersen, J.S., Mohr, F-W.:
Effects of the new antiarrhythmic peptide ZP123 on epicardial activation and repolarization pattern.
Cell Communication and Adhesion 2003. Vol. 10, pp 371-378
Kjølbye, A.L., Eloff, B.C. and Rosenbaum, D.S.:
Maintenance of intercellular coupling by ZP123 suppresses arrhythmogenic discordant alternans.
American Heart Association, Scientific Sessions 2003 9-12 Nov. 2003, Orlando, Florida, USA.
Circulation 2003, 108 (supplement IV), Abstract 1389, p IV-292
Power Point Presentation
Thorkildsen, C., Neve, S., Larsen, B. D., Meier, E., and Pedersen, J. S.:
Glucagon-Like Peptide 1 Receptor Agonist ZP10A Increases Insulin mRNA Expression and Prevents Diabetic Progression in db/db Mice.
J. Pharmacol. Exp. Ther., 2003. Vol. 307, No. 2, pp 490-496
Dhein, S., Larsen B.D. and Petersen J.S.:
Effects of the New antiarrhythmic peptide ZP123 on epicardial activation and repolarisation.
2003 International Gap Junction Conference, August 23-28, 2003, Cambridge, UK. Poster abstract p. 58
Hartvig, L., Christjansen, K.N., Hyttel, J. and Petersen, J.S.:
ZP123 prevents 18a-glycyrrhetinic acid-induced inhibition of cAMP transfer.
2003 International Gap Junction Conference, August 23-28, 2003, Cambridge, UK. Poster abstract p. 70
Poster presentation
Haugan, K., Petersen, J.S., Hartvig, L., Holstein-Rathlou, N-H. and Nielsen, M.S.:
The antiarrhythmic peptide analogue ZP123 inhibits acidosis-induced decrease in atrial conduction velocity in isolated left rat atrium.
2003 International Gap Junction Conference, August 23-28, 2003, Cambridge, UK. Poster abstract p. 70
Poster presentation
Nielsen, M.S., Marcussen, N., Jørgensen, N.K., Holstein-Rathlou, N-H., Kjølbye, A.L. and Petersen, J.S.:
ZP123 inhibits ischemia-induced cell swelling in cardiomyocytes and reduces infarct size after myocardial infarction (MI) in rats.
2003 International Gap Junction Conference, August 23-28, 2003, Cambridge, UK. Poster abstract p. 109
Kjølbye, A.L., Knudsen, C.B., Jepsen, T., Larsen, B.D. and Petersen, J.S.:
Pharmacological characterization of the new stable antiarrhythmic peptide analog Ac-D-Tyr-D-Pro-D-Hyp-Gly-D-Ala-Gly-NH2 (ZP123): In vivo and in vitro studies.
J. Pharmacol. Exp. Ther., 2003. 306, 1191-1199
Gustafsson, F., Mikkelsen H. B., Arensbak, B., Thuneberg, L., Neve, S., Jensen, L. J., Holstein-Rathlou, N-H.:
Expression of connexin 37, 40 and 43 in rat mesentaric arterioles and resistance arteries.
Histochem Cell Biol (2003) 119:139-148
Xing, D., Kjølbye, A. L., Nielsen. M.S., Petersen, J. S., Harlow, K. W., Holstein-Rathlou, N.-H. and Martins, J. B.:
ZP123 Increases Gap Junctional Conductance and Prevents Reentrant Ventricular Tachycardia During Myocardial Ischemia in Open Chest Dogs.
J. Cardiovasc. Electrophysiol. 2003. 14, 510-520.
Hansen, S. S., Henriksen, Z., Petersen, J. S., Sørensen, O. H., and Jørgensen, N. R.:
The AAP analogue ZP123 increases intercellular coupling in human osteoblasts and stimulates production of bone formation markers in vitro.
30th European Symposium on Calcified Tissues, Rome, Italy, 8-12 May, 2003, Poster abstract, No. P-93, p 358
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