
8. juni 2010:Pressemeddelelse nr. 5, 2010: Zealand Pharma Announces An Extension of The Lixisenatide...
The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010 (Science) 46th An...
Zealand Pharma entered into an agreement with Wyeth in April 2003. Under this agreement, Zealand Pharma granted Wyeth exclusive, worldwide rights to co-develop, manufacture and market Rotigaptide (ZP123) for any indication, and in February 2004 extended this to new collaborative activities relating to gap-junction modulators.
In 2007 Wyeth has finalized a global multi-centre Phase IIa safety and tolerability trial with rotigaptide in patients with large myocardial infarcts.
In October 2007 Wyeth advanced the first orally available gap junction modifier Danegaptide (ZP1609/GAP-134) into phase I clinical trials in the US. Danegaptide has shown pharmacological effects in animal models of both ventricular and atrial arrhythmias, and with its oral formulation, the molecule represents a novel paradigm for the potential chronic prevention of cardiac arrhythmias.
In 2009 Wyeth was taken over by Pfizer.
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